Mental health and sleep problems are prevalent in young people with hypermobile Ehlers-Danlos syndrome (hEDS) and have a negative impact oon their quality of life, a study suggests. Patient-reported anxiety and pain were the symptoms most closely associated with life quality impacts in a group of children and young…
Researchers cited a need for increased awareness of Ehlers-Danlos syndrome (EDS) as a risk factor for chronic pancreatitis in a recent case report. In a rare occurrence, a woman who had chronic pancreatic damage from a previous bout of acute pancreatitis experienced a new symptom attack without an obvious…
Hypoglycemia, or low blood sugar, may be among symptoms of Ehlers-Danlos syndrome (EDS), according to a case report. A woman with hypermobile EDS (hEDS) came to a clinic experiencing significant neurological symptoms related to low blood sugar that occurred most often after eating or physical activity, but was…
Researchers using a mouse model discovered two possible approaches for restoring more normal wound healing in classical Ehlers-Danlos syndrome (cEDS). Both help to beneficially modulate a network of molecules called the extracellular matrix (ECM). The ECM is important for providing structure and support to cells and for promoting wound…
Young adults with hypermobile Ehlers-Danlos syndrome (hEDS) exhibit signs of an imbalance in the body’s autonomic nervous system, according to a recent study. The autonomic nervous system is responsible for regulating involuntary bodily functions such as heart rate, blood pressure, breathing, and digestion. The observed imbalance was linked to…
People with hypermobile Ehlers-Danlos syndrome (hEDS) produced less force when extending their hips during walking and had weaker muscles associated with hip extension compared to healthy people, according to a recent analysis. Researchers believe this muscle weakness may contribute to joint instability and related joint damage that tends to…
Children with hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorder (HSD) who are in pain or anticipating pain show certain walking patterns, leading researchers to believe walking assessments may help to better understand clinical characteristics of the conditions and to develop coping strategies. Compared with typically developing children, those…
A condition called cerebral venous outflow disorder, where blood flow out of the brain is impaired, may have a unique clinical presentation when it occurs in people with connective tissue disorders such as Ehlers-Danlos syndrome (EDS), according to recent research. People with connective tissue diseases who were seen at…
Components of the extracellular matrix (ECM), the network of molecules that gives tissues their structure, are dysregulated in skin cells from people with vascular Ehlers-Danlos syndrome (vEDS), making it a possible target for therapeutic intervention, a recent study suggests. The ECM took on properties…
Abnormally high sensitivity of a type of sensory nerve fibers is behind the heightened pain responses to harmless light touch that were observed in a mouse model of classical-like Ehlers-Danlos syndrome (clEDS), a study shows. This abnormal pain sensation, called mechanical allodynia, is a main symptom of neuropathic pain…
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