hEDS-related Pain May Be Linked to Deficit in Pain Control Mechanisms, Study Shows

Pain in people with hypermobile Ehlers-Danlos syndrome (hEDS) likely is the result of an impaired pain suppression system that may lead to widespread pain, a study shows. The data, which also contradict a previous theory that EDS-related pain was caused by damage in nerve fibers, may help in the development…

Research Sheds Light on Underlying Mechanisms of Chronic Pain in Classical-like EDS

Lack of the protein tenascin X (TNX) associated with classical-like Ehlers-Danlos syndrome (EDS) promotes higher pain sensitivity to tactile and chemical stimuli and aggravates inflammatory pain, a study in mice shows. These findings add knowledge to the mechanisms behind chronic pain in classical-like EDS and may help to identify other…