Skin nodules reported for first time in EDS in case of young woman

A first case of dermatofibromas — benign and firm skin nodules, often darker than the patient’s skin color — has been reported in Ehlers-Danlos syndrome (EDS) in a young woman in Iran. “To our knowledge, this combination of findings is a previously unreported occurrence,” the researchers wrote in…

Extracellular matrix dysregulated in vEDS patients’ skin cells: Study

Components of the extracellular matrix (ECM), the network of molecules that gives tissues their structure, are dysregulated in skin cells from people with vascular Ehlers-Danlos syndrome (vEDS), making it a possible target for therapeutic intervention, a recent study suggests. The ECM took on properties…

EDS and Your Skin

Skin issues are common to people with Ehlers-Danlos syndrome (EDS). Here is more information about how EDS can affect your skin, as well as some ways in which you can manage these problems. How may EDS affect your skin? Although specific symptoms vary, most types of EDS have some degree…

Molecular Analysis Pinpoints Pathways Underlying Defects in cEDS

Gene expression analysis of skin cells identified several molecular pathways deregulated in classical Ehlers-Danlos syndrome (cEDS) patients, which may open new avenues for therapeutics, according to a new study. The study, “Molecular insights in the pathogenesis of classical Ehlers-Danlos syndrome from transcriptome-wide expression profiling of patients’ skin fibroblasts,” was…