José Lopes, PhD, managing science editor —

Patients with mutations in the COL5A1 and COL1A1 genes that code for collagen proteins have both Ehlers-Danlos syndrome (EDS) and a bone disease called osteogenesis imperfecta (OI), according to a study in a Chinese family. The research, “Compound phenotype of osteogenesis imperfecta and Ehlers-Danlos…

Generex Biotechnology will launch a wound care gel formulation called Excellagen, a potential treatment option for patients with Ehlers-Danlos syndrome (EDS) among others disorders. Excellagen is a highly-purified type 1 collagen-based, topical gel. According to Generex, its 3D dermal matrix favors wound healing. It activates platelets, leading to the…

A patient with vascular Ehlers-Danlos syndrome (vEDS) and a type of abnormal communication between blood vessels called carotid-cavernous fistula (CCF) was successfully treated via selective shunt occlusion, according to a case report. The study, “Selective Shunt Occlusion of Direct Carotid-Cavernous Fistula with Vascular Ehlers-Danlos Syndrome…

Patients with hypermobile Ehlers-Danlos syndrome (hEDS) have an increased prevalence and severity of gastrointestinal (GI) symptoms, and use more potentially damaging medications than healthy people without the disorder, according to a new study. The data also showed that hEDS patients have a worse quality of life than patients with …

A protein called tenascin X (TNX) plays a key role in gut motility and sensitivity to pain, according to a study in mice and in patients with hypermobile Ehlers-Danlos syndrome (hEDS). The findings also link a TNX deficiency to increased abdominal pain, constipation, and diarrhea in hEDS patients.

A patient with vascular Ehlers-Danlos syndrome (vEDS), recurrent pneumothorax, and other atypical pulmonary complications was described in a case report from South Korea. The case study, “Vascular Ehlers-Danlos syndrome with cryptorchidism, recurrent pneumothorax, and pulmonary capillary hemangiomatosis-like foci, A case report,” was published in the…

Patients with Ehlers-Danlos syndrome (EDS) showed a low recurrence rate after hernia surgery, possibly due to the large mesh size used in the procedure, according to researchers. Their study, “Complications and recurrence rates of patients with Ehlers-Danlos syndrome undergoing ventral hernioplasty: a case series,” was published…