Lack of TNX Protein Impairs Gut Motility, Increases GI Symptoms in Hypermobile Patients, Study Reports
A protein called tenascin X (TNX) plays a key role in gut motility and sensitivity to pain, according to a study in mice and in patients with hypermobile Ehlers-Danlos syndrome (hEDS). The findings also link a TNX deficiency to increased abdominal pain, constipation, and diarrhea in hEDS patients.