Author Archives: Forest Ray PhD

Researchers With EDS May Have Found Causative hEDS Mutation

Scientists finally may have discovered a gene mutation that associates with hypermobile Ehlers-Danlos syndrome (hEDS) — and their findings, eagerly awaited by the hEDS patient community, are expected to be written up within the next six months, they said. While known mutations are linked with various EDS subtypes, hEDS cases…

Aytu BioPharma Acquires License to Develop DB102 for vEDS

Aytu BioPharma has acquired the option to license DB102 (enzastaurin), an investigational anti-tumor therapy with the potential to treat vascular Ehlers-Danlos syndrome, or vEDS. Denovo Biopharma, which holds worldwide rights to DB102 — originally developed as an oncology treatment — will continue to develop the oral therapy…

EDS-related Gene Variants Found to Play Role in Eye Disorder

Genes involved in Ehlers-Danlos syndrome (EDS) appear to play a role in keratoconus (KC) — a thinning of the eye’s cornea. This finding, from a recent study, is the first to demonstrate shared genetic variations between the two disorders although their association has been suggested. The study, “…

Certain Complications More Common in Hospitalized EDS Patients

Hospitalized patients with Ehlers-Danlos syndrome (EDS) experience more gastrointestinal (GI), cardiovascular, nervous, and allergic conditions than those without EDS, a recent study has found. The findings suggest physicians should consider the possibility of EDS and exercise appropriate precautions when examining patients in whom these conditions have no other apparent…

Rare Vascular Case of EDS Linked to Newly Identified Mutation

Physicians should suspect vascular Ehlers-Danlos syndrome when a patient shows recurrent pulmonary complications and unusually thin skin and hypermobile joints, a case report suggests. The patient was found to have a previously unknown gene mutation that affected a connective tissue protein, its investigators wrote. Their report, “Recurrent pneumothorax and…