News

Immune system changes linked to hypermobile EDS in new study

Hypermobile Ehlers-Danlos syndrome (EDS) is not just a problem of the connective tissue that provides structure to the body, but also involves changes in the immune response, which could provide opportunities to improve diagnosis and treatment, a study finds. “Our study provides strong evidence that immune dysregulation plays a…

Prolotherapy shows promise for sacroiliac joint instability in EDS

Prolotherapy, a type of regenerative medicine, may be a promising option to treat sacroiliac joint instability in people with Ehlers-Danlos syndrome (EDS), according to a small study. Treatment reduced self-reported pain in the sacroiliac joint, where the spine meets the pelvis, and improved the functional outcomes of patients,…

Gene mutations undermine connective tissue structure in spEDS

Mutations in the B3GALT6 gene, a cause of spondylodysplastic Ehlers-Danlos syndrome (spEDS), disrupt the maturation of a type of collagen protein, undermining the structure and strength of connective tissue, according to a new study. These findings “may have a significant impact on the clinical expression of spEDS and advance…

Undiagnosed vEDS revealed as cause of man’s perforated colon

A 25-year-old man’s perforated colon was the result of an undiagnosed case of vascular Ehlers-Danlos syndrome (vEDS), according to a case study from Portugal. “In the absence of colonic disease and with clinical manifestations of connective tissue disorders, a genetic investigation for vEDS should be conducted, even in individuals…

Teens with hypermobile Ehlers-Danlos have more fatigue: Study

Adolescents with hypermobile Ehlers-Danlos syndrome (hEDS) are less active than their peers and tend to have more fatigue and negative mentalities about pain, a study reports. While hypermobile participants spent significantly more of their waking hours engaged in sedentary behavior and less in moderate-to-vigorous physical activity, they moved a…

Overlooked CT scan clue shows cerebral air embolism with vEDS

A young man with vascular Ehlers-Danlos syndrome (EDS) developed a cerebral air embolism caused by air entering blood vessels in his brain that was difficult to diagnose and illustrated the importance of carefully reviewing CT scans. “Prompt identification of cerebral air embolism allows supportive measures to be started to…