News

Vascular Ehlers-Danlos syndrome (vEDS) does not appear to increase the risk of life-threatening complications during pregnancy and delivery, according to a study in the Netherlands that looked at data from 121 pregnancies. However, about 1 in 5 of those pregnancies ended in miscarriage, a rate about twice as high…

Findings from a tailored, online Pilates program suggest that participating in exercise may help people with hypermobile Ehlers–Danlos syndrome (hEDS) and those with hypermobile spectrum disorder (HSD) feel stronger and more empowered. An “online exercise may be a valuable modality to help people with chronic conditions remain active,” wrote…

People with hypermobile Ehlers-Danlos syndrome (EDS) often have abnormalities such as small gaps in the upper part of their spine and may hold their heads differently than individuals without the disorder, according to a study that suggests these differences could help with diagnosis and treatment. The study, “Head…

Mental health concerns, including depression and anxiety, are highly prevalent among people with Ehlers-Danlos syndrome (EDS) and generalized hypermobility spectrum disorder (G-HSD), according to a retrospective study. “Given the prevalence of mental health concerns in this population, it is critical to provide mental health support to patients with EDS…

An interaction between the proteins M2K6, p38, and ERK may substantially affect the risk of major bleeding problems in vascular Ehlers-Danlos syndrome (vEDS), and targeting them may help preserve blood vessel health, a study in mice suggests. “The findings presented in this work suggest that pharmacologic strategies that can…

People with classical-like Ehlers-Danlos syndrome type 1 (clEDS1) have an increased risk of gastrointestinal tract (GI) complications, according to a new case series. Ten of the 15 investigated patients had at least one spontaneous intestinal perforation and nearly all had diverticulosis, or small pouches that push outward through weak…

People with hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobility spectrum disorder (HSD) experience an earlier onset of pain, which typically affects more body areas and with a longer duration, than individuals with pain due to other conditions. Those are the findings of a new study by researchers in Sweden, who…

Two years of daily irbesartan, a long-acting oral blood pressure medication, reduced the risk of severe arterial events by 50% in adults with vascular Ehlers-Danlos syndrome (vEDS). That’s according to the results of the Phase 3 ARCADE (NCT02597361) trial, which tested the medicine on a background of celiprolol,…

Insomnia and depression strongly contribute to the chronic fatigue that affects about 80% of adults with  hypermobile Ehlers-Danlos syndrome (hEDS), interfering with their daily functioning and mental health, a study in Italy shows. The study compared fatigue between people with hEDS and those with another condition that also affects…

People with Ehlers-Danlos syndrome (EDS) can safely undergo total joint replacement surgery and achieve significant gains, among them “[improved] quality of life in … patients who had marked arthritis,” according to a new review. However, EDS patients who have this procedure — known as arthroplasty, it’s when a joint such…