News

An interaction between the proteins M2K6, p38, and ERK may substantially affect the risk of major bleeding problems in vascular Ehlers-Danlos syndrome (vEDS), and targeting them may help preserve blood vessel health, a study in mice suggests. “The findings presented in this work suggest that pharmacologic strategies that can…

People with classical-like Ehlers-Danlos syndrome type 1 (clEDS1) have an increased risk of gastrointestinal tract (GI) complications, according to a new case series. Ten of the 15 investigated patients had at least one spontaneous intestinal perforation and nearly all had diverticulosis, or small pouches that push outward through weak…

People with hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobility spectrum disorder (HSD) experience an earlier onset of pain, which typically affects more body areas and with a longer duration, than individuals with pain due to other conditions. Those are the findings of a new study by researchers in Sweden, who…

Two years of daily irbesartan, a long-acting oral blood pressure medication, reduced the risk of severe arterial events by 50% in adults with vascular Ehlers-Danlos syndrome (vEDS). That’s according to the results of the Phase 3 ARCADE (NCT02597361) trial, which tested the medicine on a background of celiprolol,…

Insomnia and depression strongly contribute to the chronic fatigue that affects about 80% of adults with  hypermobile Ehlers-Danlos syndrome (hEDS), interfering with their daily functioning and mental health, a study in Italy shows. The study compared fatigue between people with hEDS and those with another condition that also affects…

People with Ehlers-Danlos syndrome (EDS) can safely undergo total joint replacement surgery and achieve significant gains, among them “[improved] quality of life in … patients who had marked arthritis,” according to a new review. However, EDS patients who have this procedure — known as arthroplasty, it’s when a joint such…

Including the experiences and needs of people with hypermobile Ehlers-Danlos syndrome (hEDS) or generalized hypermobility spectrum disorder (HSD) in treatment planning could lead to better care, and this could translate into better quality of life for these patients, the findings of a new U.S. survey study suggest. “The current…

More than half of children with vascular Ehlers-Danlos syndrome (vEDS) are diagnosed through genetic testing after a family member is found to have the disease, a study found. The remaining patients receive their diagnosis following a serious clinical event that requires medical intervention or due to having certain clinical…

Within three months of an Ehlers-Danlos syndrome (EDS) diagnosis, many patients and their parents felt there was a lack of related educational materials, which was a barrier to their knowledge and comfort in managing the condition, according to a new survey study conducted by U.S. researchers. The respondents also…

People with Ehlers-Danlos syndrome (EDS) living in the U.S. face high healthcare costs, with the annual median out-of-pocket expense exceeding $13,000, a study found. The findings “highlight the magnitude of the burden of health care spending on patients with EDS,” with “both direct and indirect costs of accessing and…