Warning Signs of Depression in People With EDS

Emily Malcolm, PhD avatar

by Emily Malcolm, PhD |

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Being diagnosed with a chronic illness, such as Ehlers-Danlos syndrome (EDS), can be stressful and lead to depression in patients and their families. Patients may feel that they’ve lost control of their lives after their diagnosis, which can make them feel anxious.

Practicing self-care is important to maintain good health. If you experience any of the following signs of depression, talk to a doctor about the different treatment options available.

Feelings of hopelessness or despair

Feeling down occasionally is normal, but if you feel hopeless and despair most of the time, you may be clinically depressed.

Lost interest in hobbies

If you’ve lost interest in hobbies that previously were important and enjoyable to you, or if you find it hard to connect with friends and family, you may be experiencing signs of depression.

Weight and appetite changes

Rapid changes in weight — loss or gain — may indicate that something is wrong mentally. Depression can cause some people to lose their appetite, and others to increase their appetite for unhealthy or “comfort” foods.

Sleep changes

Depression can cause people to have insomnia, or difficulty falling or staying asleep. Others may have difficulty waking up.

Mood changes

Feelings of agitation or restlessness, and the feeling of being in danger of losing your temper over minor things, can be signs of depression.

Guilt or self-loathing

Another sign of depression is feeling guilty for no reason, or putting yourself down, either to yourself or when talking to others.

Concentration problems

Trouble focusing on problems or tasks, and forgetfulness can be signs of depression.

Aches or pains

Depression can lead to physical symptoms, including back problems, stomach pains, or general aches. EDS can also lead to chronic pain, which is hampered by depression. Talk to your doctor about any pains you are experiencing.

Feeling suicidal

Depression is a major risk factor for suicide. If you have suicidal thoughts, seek help as soon as possible. In the U.S., the National Suicide Hotline provides 24-hour support by phone, text, or online chat.


Last updated: Jan. 30, 2020


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